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Projects

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At present, materials technology is one of the most promising fields in prosthesis. TEQUIR led a consortium with Spanish research centres (IBV, CBIT-UPV and INASMET-TECNALIA) to develop new biomaterials to be used in bone fusion. This consortium was involved in a CENIT INTELIMPLANT project (Advanced Biomaterials for a New Generation of Implants) led by BTI (Biotechnology Institute, S.L.). As a result of this project, a new biomaterial with promising properties in the regeneration of bone defects was developed. The project reached the synthesis stage of different biopolymers, their biological in vivo and in vitro evaluation and their mechanical evaluation. All these tests were carried out comparing them with a commercially available control commercial material with a similar functionality.

After the densitometry studies and 3D reconstruction, and the mechanical tests, no significant differences were founded in the newly-formed bone tissue as a result of repairing the generated defect, neither between the employed biomaterials (including the control material) nor between the test periods (8 and 16 weeks).

The behaviour of all test biomaterials (including the control material) is very similar both in the short term and the long term, and in all cases there is practically a full recovery of the mechanical resistance of the bone in comparison with healthy tissue. The fact that new biomaterials developed in the project achieve bone tissue regeneration in critical size defect comparable to that of the control material is a very positive result and indicates that any of these treatments could be used in the clinical application of vertebral fusions. As a result of the project, the enterprise has a new biomaterial that in the near future could reach the market, increasing the enterprise competitiveness.

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